Kingsley Yin,   PhD

Education

University of Western Australia, Australia
PhD (Medicine) , 1991

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Honors and Awards

1989-1990,   National Heart Foundation of Australia

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Publications

Yin K, Gribbin E, Wang H Interferon-gamma inhibition attenuates lethality after cecal ligation and puncture in rats: implication of high mobility group box-1. Shock. Vol. 2005 Oct;24(4): 396-401 (2005 ) .

Yin K, Gribbin E of IFN-gamma in tissue repair, bacterial load and organ injury after CLP. Shock. Vol. 2004;21: 21-21 (2004 ) .

Wang C, Kuzma M, Qiu G, Yin K Heterogenous and compartment-specific activation of nonlymphocytic, mononuclear cells in intraabdominal sepsis. Exp Lung Res. Vol. Oct-Nov 2003;29(7): 503-521 (2003 ) .

Qiu G, Gribbin E, Harrison K, Sinha N, Yin K Inhibition of gamma interferon decreases bacterial load in peritonitis by accelerating peritoneal fibrin deposition and tissue repair. Infect Immun. Vol. May 2003;71(5): 2766-2774 (2003 ) .

Yue G, Wang H, Luo M, Yin K,et al Detection of a large number of specific mRNA species in very few glial cells. American Journal of Human Genetics. Vol. Oct 2002;71(4): 322-322 (2002 ) .

Yue G, Lai PS, Yin K, et al Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production. J Pharmacol Exp Ther. Vol. Jun 2001;297(3): 915-925 (2001 ) .

Qiu G, Wang C, Smith R, Harrison K, Yin K Role of IFN-gamma in bacterial containment in a model of intra-abdominal sepsis. Shock. Vol. Dec 2001;16(6): 425-429 (2001 ) .

Sun FF, Lai PS, Yue G, Yin K,et al Pattern of cytokine and adhesion molecule mRNA in hapten-induced relapsing colon inflammation in the rat. Inflammation. Vol. Feb 2001;25(1): 33-45 (2001 ) .

Yin K, Wilmanski J, Wang C, Qiu G, Tahamont M Lung compartmentalization of inflammatory cells in sepsis. Inflammation. Vol. Dec 2000;24(6): 547-557 (2000 ) .

Hock CE, Walker JM, Rhee S, Yin K, Rodriguez A, Spur BW Dietary lipids alter nitric oxide production and ventricular fibrillation (VF) in myocardial ischemia-reperfusion (I/R). Faseb Journal. Vol. Mar 15 2000;14(4): A685-a685 (2000 ) .

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Grants and Contracts

Title: Role of IFN-yin immunosuppression in sepsis
Sponsor: Groff Foundation
Effective Date(s): 2007 - 2008
Role: Principal Investigator

Title: Role of IFN-y inhibition in preventing anastomotic leak
Sponsor: Groff Foundation
Effective Date(s): 2005 - 2007
Role: Principal Investigator

Title: Lung Inflammation in a model of one-lung ventilation
Sponsor: Groff Foundation
Effective Date(s): 2004 - 2006
Role: Principal Investigator

Title: IFN-gamma and HMGB1 in sepsis
Sponsor: UMDNJ Foundation
Effective Date(s): 2004 - 2005
Role: Principal Investigator

Title: "Beneficial effects of Interferon-y antibody on tissue repair and bacterial containment in a model of intra-abdominal sepsis"
Sponsor: Lindback Foundation Minority Faculty Development Award Grant
Effective Date(s): 2002 - 2003
Role: Principal Investigator

Title: "Lung Inflammation in Sepsis"
Sponsor: American Heart Association, Heritage Affilaite
Effective Date(s): 2000 - 2004
Role: Principal Investigator

Title: "Receptor G-protein coupling in the heart"
Sponsor: NIH
Effective Date(s): 1997 - 2000
Role: Principal Investigator

Title: "Role of IFN-y on lung inflammation in sepsis"
Sponsor: UMDNJ Foundation
Effective Date(s): 1999 - 2000
Role: Principal Investigator

Title: "Role of free radicals in endotoxin shock"
Sponsor: American Heart Association, NJ Affiliate
Effective Date(s): 1995 - 1997
Role: Principal Investigator

Title: "Transcellular eicosanoid metabolism of bowel inflammation"
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases
Effective Date(s): 1994 - 1996
Role: Co-Principal Investigator

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Research Areas

Interferon-gamma in bacterial containment and wound healing during sepsis.Regulation of the activity of mononuclear cells in the lung during sepsis. :

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