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Susan Muller-Weeks,   PhD


Assistant Professor

Molecular Biology


Office Address:

Science Center, Room 129
Two Medical Center Drive

Stratford NJ -   08084

Contact:

Tel: 856-566-6098
Fax: 856-566-6291

muller@umdnj.edu

Education

Rutgers College, NJ
BA (Biology) , 1986

Rutgers University, NJ
PhD (Cell and Molecular Biology) , 1992

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Honors and Awards

2004,   Lindback Distinguished Teaching Award

1989,   NJ Commission on Cancer Reserch Pre-doctoral Fellowship

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Publications

Boesze-Battaglia K, Stefano FP, Fitzgerald C., and Muller-Weeks S. ROM-1 potentiates photoreceptor specific membrane fusion processes.. Exp Eye Res. . Vol. 84: 22-31 (2007 ) .

Fischer, J.A., Muller-Weeks, S., and Caradonna, S. Fluorodeoxyuridine modulates cellular expression of the DNA base-excision repair enzyme, uracil-DNA glycosylase.. Cancer Research . Vol. 66: 8829- 8837 (2006 ) .

Muller-Weeks, S., Balzer, R., Fitzgerald, R., Caradonna, S. Proliferation dependent expression of nuclear uracil-DNA glycosylase is mediated in part by E2F-4.. DNA Repair. Vol. 4: 183-190 (2005 ) .

Fischer JA, Muller-Weeks S, Caradonna S Proteolytic degradation of the nuclear isoform of uracil-DNA glycosylase occurs during the S phase of the cell cycle. DNA Repair (Amst). Vol. May 4 2004;3(5): 505-513 (2004 ) .

Mandola MV, Stoehlmacher J, Muller-Weeks S, et al A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity. Cancer Res. Vol. Jun 1 2003;63(11): 2898-2904 (2003 ) .

Elateri I, Tinkelenberg BA, Hansbury M, Caradonna S, Muller-Weeks S, Ladner RD hSMUG1 can functionally compensate for Ung1 in the yeast Saccharomyces cerevisiae. DNA Repair (Amst). Vol. Mar 1 2003;2(3): 315-323 (2003 ) .

Elateri I, Muller-Weeks S, Caradonna S The transcription factor, NFI/CTF plays a positive regulatory role in expression of the hSMUG1 gene. DNA Repair (Amst). Vol. Dec 9 2003;2(12): 1371-1385 (2003 ) .

Muller-Weeks S, Boesze-Battaglia K, Fitzgerald C Deletional analysis of the rod photoreceptor cell peripherin/RDS carboxy-terminal region. Exp Eye Res. Vol. Aug 2002;75(2): 143-154 (2002 ) .

Caradonna S, Muller-Weeks S The nature of enzymes involved in uracil-DNA repair: isoform characteristics of proteins responsible for nuclear and mitochondrial genomic integrity. Curr Protein Pept Sci. Vol. Dec 2001;2(4): 335-347 (2001 ) .

Stefano FP, Muller-Weeks S, Marta P, Krouse J, Boesze-Battaglia K Characterization of C-terminal peripherin/rds mutations in a heterologous MDCK cell expression system. Investigative Ophthalmology & Visual Science. Vol. Mar 15 2001;42(4): S656-S656 (2001 ) .

Muller-Weeks S, Fitzgerald C, McFadden K, Boesze-Battaglia K Analysis of rom-1 function and regulation. Investigative Ophthalmology & Visual Science. Vol. Mar 15 2001;42(4): S656-S656 (2001 ) .

Fitzgerald C, McCorkell K, Muller-Weeks S Characterization of the human rom-1 promoter. Investigative Ophthalmology & Visual Science. Vol. Mar 15 2000;41(4): S391-S391 (2000 ) .

Muller-Weeks S, Balzer RJ, Anderson R, Caradonna S Proliferation-dependent expression of nuclear uracil-DNA glycosylase is mediated in part by E2F-4. DNA Repair (Amst). Vol. Feb 3 2005;4(2): 183-190 (2000 ) .

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Grants and Contracts

Title: Post translational mechanisms in uracil-DNA repair
Sponsor: National Institutes of Health - National Cancer Institute
Effective Date(s): 2000 - 2005
Role: Co-Investigator

Title: Peripherin/rds Mutations and Retinal Degeneration
Sponsor: NIH: Academic Research Enhancement Award
Effective Date(s): 1998 - 2002
Role: P.I.

Title: Transcriptional regulation of the retinal specific rom-1 gene
Sponsor: UMDNJ Foundation
Effective Date(s): 2000 - 2001
Role: P>I>

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Research Areas

Cell cycle control mechanisms and DNA Repair; gene regulation: Cell cycle control mechanisms and DNA Repair; gene regulation

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