Peitan Liu,   PhD

Education

University of Surrey , UK
PhD (Department of Biochemistry) , 1992

Fourth Medical College, Xi'an, China
MD (Medicine) , 1970

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Honors and Awards

1998-1999,   The 1998-9999 Foundation Awards for Excellence in Teaching, UMDNJ-SOM

1997-1999,   American Heart Association Affiliate Grant-In-Aid

1990-1992,   Fellowship by The Sir Halley Stewart Trust, UK

1987-1988,   Fellowship by the Royal Society, UK

1988,   Visiting Scholar Grant, Kurume Medical College, Japan

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Publications

Peitan Liu, Baohuan Xu, Thomas A. Cavalieri, and Carl E. Hock. Inhibition of p53 by pifithrin-a reduces myocyte apoptosis and leukocyte transmigration in aged rat hearts following 24 hours of reperfusion. Shock. Vol. 30: 545-551 (2008 ) .

Peitan Liu, Bashuan Xu, Thomas A. Cavalieri, Carl E. Hock Inhibition of p53 by pifithrin-alpha improves cardiac function in aged rats following myocardial ischemia reperfusion.. Shock. Vol. 17: 185-192 (2006 ) .

Liu PT, Xu B, Cavalieri TA, Hock CE Attenuation of antioxidative capacity enhances reperfusion injury in aged rat myocardium after MI/R. Am J Physiol Heart Circ Physiol. Vol. Dec 2004;287(6): H2719-2727 (2004 ) .

Liu PT, Xu BC, Cavalieri TA, Hock CE Affects of aging on oxidative stress and inflammation in rat model of MI/R. Faseb Journal. Vol. Mar 17 2003;17(5): A842-a842 (2003 ) .

Liu PT, Xu B, Forman LJ, Carsia R, Hock CE L-NAME enhances microcirculatory congestion and cardiomyocyte apoptosis during myocardial ischemia-reperfusion in rats. Shock. Vol. Mar 2002;17(3): 185-192 (2002 ) .

Liu PT, Xu BH, Cavalieri TA, Hock CE Age-related difference in myocardial function and inflammation in a rat model of myocardial ischemia-reperfusion. Cardiovascular Research. Vol. Dec 2002;56(3): 443-453 (2002 ) .

Hock CE, Liu PT, Patel R, et al Effect of dietary unsaturates on plasma cytokines and tissue superoxide following myocardial ischemia-reperfusion (I/R). Faseb Journal. Vol. Mar 22 2002;16(5): A856-a856 (2002 ) .

Huck CE, Liu PT, Walker JM, Xu BH, Rodriguez A, Dietary lipids modulate arrhythmias and the inflammatory response following myocardial isehemia-reperfusion (I/R). Faseb Journal. Vol. Mar 8 2001;15(5): A769-a769 (2001 ) .

Liu PT, Xu B, Hock CE Inhibition of nitric oxide synthesis by L-name exacerbates acute lung injury induced by hepatic ischemia-reperfusion. Shock. Vol. Sep 2001;16(3): 211-217 (2001 ) .

Liu PT, Xu B, Spokas E, Lai PS, Wong PY Role of endogenous nitric oxide in TNF-alpha and IL-1beta generation in hepatic ischemia-repefusion. Shock. Vol. Mar 2000;13(3): 217-223 (2000 ) .

Xu BH, Liu PT, Wong PYK L-NAME enhances no-reflow phenomenon and myocyte apoptosis in myocardial ischemia-reperfusion in rats. Faseb Journal. Vol. Mar 15 2000;14(4): A685-a685 (2000 ) .

Liu PT, Xu BH, Wong PYK Nitric oxide modulates apoptosis signal transduction in myocardial ischemia-reperfusion in rats. Faseb Journal. Vol. Mar 15 2000;14(4): A685-a685 (2000 ) .

Liu PT, Xu BH, Quilley J, Wong PYK Peroxynitrite attenuates hepatic ischemia-reperfusion injury. American Journal of Physiology-Cell Physiology. Vol. Dec 2000;279(6): C1970-C1977 (2000 ) .

Liu PT, Xu B, Quilley J, Wong PY Peroxynitrite attenuates hepatic ischemia-reperfusion injury. Am J Physiol Cell Physiol. Vol. Dec 2000;279(6): C1970-1977 (2000 ) .

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Grants and Contracts

Title: "Pifithrin-alpha improves cardiac function and reduces myocyte apoptosis in aged rats following myocardial ischemia-reperfusion"
Sponsor: UMDNJ-SOM Foundation
Effective Date(s): 2004 - 2005
Role: Principal Investigator

Title: "Affects of aging on myocardial MDM2/MDMx expression in a rat model of myocardial ischemia-reperfusion"
Sponsor: intramural Funding Program, Aging Center, UMDNJ
Effective Date(s): 2003 - 2004
Role: Principal Investigator

Title: "Effects of aging on p53/Bax-medicated myocyte apoptosis in a rat model of myocardial ischemia-reperfusion"
Sponsor: Lindback Awards Program
Effective Date(s): 2003 - 2004
Role: Principal Investigator

Title: " Apoptosis signal transduction in rat hearts after myocardial ischemia-reperfusion: age-associated difference"
Sponsor: UMDNJ, Aging Center
Effective Date(s): 2000 - 2002
Role: Principal Investigator

Title: "NO modified apoptosis signal trasduction in myocardial ischemia-reperfusion: age-associated difference"
Sponsor: UMDNJ Foundation
Effective Date(s): 2000 - 2002
Role: Principal Investigator

Title: "Role of nitric oxide in hepatic ischemia reperfusion"
Sponsor: American Heart Association Affiliate Grant-In-Aid
Effective Date(s): 1997 - 1999
Role: Principal Investigator

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Research Areas

Inflammation induced by ischemia/reperfusion of individual organs(the heart or liver in rats), and the role of the various inflammatory mediators, such as nitric oxide, TNF-alpha, and adhesion molecules (P-selectin, ICAM-1) in the inflammatory injury: Present focus is on the role of nitric oxide in the modulation of activation of apoptosis pathways in the rat model of myocardial ischemia-reperfusion.

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