Xinhua Chen,   MD, MS

Education

Shanghai Second Medical University, China
MD (Medicine) , 1977

University of Pennsylvania, PA
MS (Clinical Epidemiology) , 1993

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Publications

Theresa O. Scholl, Xinhua Chen Vitamin D intake during pregnancy: Association with maternal characteristics and infant birth weight . Early Human Development. Vol. 85: 231-4 (2009 ) .

Stein TP, Scholl TO, Schluter MD, Leskiw MJ, Chen X Oxidative stress early in pregnancy and pregnancy outcome. Free Rad Res. Vol. 42: 841-848 (2008 ) .

Bottalico JN, Chen X, Tartaglia M, Rosario B, Yarabothu D, Nelson L Second Trimester Genetic Sonogram for the Detection of Fetal Chromosomal Abnormalities in a Community Hospital Setting. Ultrasound in Obstet Gynecol . Vol. : (2008 ) .

Chen X, Scholl TO Association of elevated free fatty acids during late pregnancy with preterm delivery. Obstet Gynecol . Vol. 112: 297-303 (2008 ) .

Scholl TO, Chen X, Sims M, Stein TP Vitamin E: maternal concentrations are associated with fetal growth. AJCN. Vol. 84: 1442-8 (2006 ) .

Bogden JD, Kemp FW, Chen X, Stagnaro-Green A, Stein TP, Scholl TO Low-normal serum selenium early in human pregnancy predicts lower birth weight. Nutr Res . Vol. 26: 497-502 (2006 ) .

Chen X, Scholl TO, Stein TP. Association of elevated serum ferritin levels and the risk of gestational diabetes mellitus in pregnant women - Camden Study. . Diabetes Care . Vol. 29: 1077-82 (2006 ) .

Chen X, Scholl TO. Oxidative stress: changes in pregnancy and with gestational diabetes mellitus. . Current Diabetes Reports . Vol. 5: 282-8 (2005 ) .

Scholl TO, Leskiw M, Chen X, Sims M, Stein TP. Oxidative stress, diet and the etiology of preeclampsia.. AJCN. Vol. 81: 1390-6. (2005 ) .

Stagnaro-Green A, Chen X, Bogden JD, Davies, TF, Scholl TO. The thyroid and pregnancy; a novel risk factor for very preterm delivery. . Thyroid . Vol. 15: 351-7 (2005 ) .

Johnson WG, Scholl TO, Spychala JR, Stenroos ES, Chen X. Common dihydrofolate reductase 19-base pair deletion allele: a novel risk factor for preterm delivery. . AJCN . Vol. 81: 664-8 (2005 ) .

Chen X, Scholl TO, Leskiw MJ, Donaldson MR, Stein TP. Author's response: Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. . J Clin Endocrinol Metab . Vol. 89: 4773-4 (2004 ) .

Scholl TO, Chen X, Khoo CS, Lenders C The dietary glycemic index during pregnancy: influence on infant birth weight, fetal growth and biomarkers of carbohydrate metabolism. . AJE . Vol. 159: 467-74 (2004 ) .

Chen X, Scholl TO, Leskiw MJ, Donaldson MR, Stein TP Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. . J Clin Endocrinol Metab . Vol. 88: 5963-8 (2003 ) .

Scholl TO, Chen X, Gaughan C, Smith W. . Maternal glucose: influence on the ethnic difference in birth weight and pregnancy outcome. . Am J Epidemiol . Vol. 156: 498-506 (2002 ) .

Scholl TO, Chen X. Insulin and the Thrifty Woman: the influence of insulin during pregnancy on gestational weight gain and postpartum weight retention. . Maternal and Child Health Journal . Vol. 6: 255-61 (2002 ) .

Chen X, Scholl TO. Ethnic differences in C-peptide/insulin/glucose dynamics in young pregnant women. . J Clin Endo Metabol . Vol. 87: 4642-6 (2002 ) .

Sowers MF, Scholl TO, Grewal J, Chen X, Jannausch M. Insulin-like growth factor-1 (IGF-1), osteocalcin and bone change in pregnant normotensive and pre-eclamptic women. . J Clin Endocrinol Metabol 2001;86:5898-5903.. Vol. 86: 5898-5903 (2001 ) .

Boden G, Chen X, Stein TP Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus. . Am J Physiol Endocrinol Metab . Vol. 280E: 23030 (2001 ) .

Boden G, Chen X, Capulong E, Mozzoli M. Effects of free fatty acids on gluconeogensis and autoregulation of glucose production in type 2 diabetes. . Diabetes . Vol. 50: 810-16 (2001 ) .

Homko C, Sivan E, Chen X, Reece EA and Boden G. Insulin secretion during and after pregnancy in patients with gestational diabetes mellitus. . J Clin Endocrinol Metabol . Vol. 86: 568-73 (2001 ) .

Scholl TO, Sowers MF, Chen X, Lenders C. Maternal glucose influences fetal growth, gestation and maternal complications. . Am J Epidemiol . Vol. 154: 514-20 (2001 ) .

Chen X, Iqbal N, Boden G. Effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects. . J Clin Invest . Vol. 103: 365-72 (1999 ) .

Boden G and Chen X. Effects of fatty acids and ketone bodies on basal insulin secretion in type 2 diabetes.. Diabetes . Vol. 48: 577-83 (1999 ) .

Sivan E, Homko CJ, Chen X, Reece EA, Boden G. Effect of insulin on fat metabolism during and after normal pregnancy. . Diabetes . Vol. 48: 834-38 (1999 ) .

Boden G, Chen X, Polansky M. Disruption of circadian insulin secretion is associated with reduced glucose uptake in first-degree relatives of patients with type 2 diabetes. . Diabetes . Vol. 48: 2182-88 (1999 ) .

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Grants and Contracts

Title: Cardiovascular risk factors and preterm delivery
Sponsor: NIH
Effective Date(s): 2009 - 2011
Role: PI

Title: Vitamin D Status in Pregnant Women
Sponsor: NIH-NICHD
Effective Date(s): 2008 - 2010
Role: Co-PI

Title: Impaired Glucose Challenge Test & Maternal-Fetal Outcomes
Sponsor: NIH-NIDDK
Effective Date(s): 2007 - 2009
Role: PI

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Research Areas

Nutrition and metabolism : 1. Carbohydrate and lipid metabolism in type 2 diabetes, gestational diabetes and obesity 2. Causes / risk factors / mechanisms on adverse pregnancy outcomes

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