Xinhua Chen, MD, MS
Assistant Professor
Obstetrics & Gynecology
Office Address:
Two Medical Center Drive
Science Center, Suite 390
Stratford
NJ
- 08084
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Contact:
Tel: 856-566-6350
Fax: 856-566-6351
chenx1@umdnj.edu
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Education
Shanghai Second Medical University,
China
MD
(Medicine)
, 1977
University of Pennsylvania,
PA
MS
(Clinical Epidemiology)
, 1993
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Publications
Chen X, Scholl TO, Stein TP Hypoadiponectinemia during pregnancy: Association with risk of varying degrees of gestational hyperglycemia and with maternal ethnicity.
J Diabetes Mellitus . Vol. 2.2: 196-202
(2012
)
.
Scholl TO, Chen X, Goldberg GS, Khusial PR, Stein TP. Maternal Diet, C-reactive protein, and the outcome of pregnancy..
J Am Coll Nutr . Vol. 30: 233-40
(2011
)
.
Chen X, Scholl TO, Leskiw M, Savaille J, Stein TP Differences in maternal circulating fatty acids composition and dietary fat intake in women with gestational diabetes or mild gestational hyperglycemia..
Diabetes Care. Vol. 33: 2049-54
(2010
)
.
Theresa O. Scholl, Xinhua Chen Vitamin D intake during pregnancy: Association with maternal characteristics and infant birth weight .
Early Human Development. Vol. 85: 231-4
(2009
)
.
Bottalico JN, Chen X, Tartaglia M, Rosario B, Yarabothu D, Nelson L Second Trimester Genetic Sonogram for the Detection of Fetal Chromosomal Abnormalities in a Community Hospital Setting.
Ultrasound in Obstet Gynecol . Vol. 33: 161-8
(2009
)
.
Chen X, Scholl TO Association of elevated free fatty acids during late pregnancy with preterm delivery.
Obstet Gynecol . Vol. 112: 297-303
(2008
)
.
Stein TP, Scholl TO, Schluter MD, Leskiw MJ, Chen X Oxidative stress early in pregnancy and pregnancy outcome.
Free Rad Res. Vol. 42: 841-848
(2008
)
.
Scholl TO, Chen X, Sims M, Stein TP Vitamin E: maternal concentrations are associated with fetal growth.
AJCN. Vol. 84: 1442-8
(2006
)
.
Bogden JD, Kemp FW, Chen X, Stagnaro-Green A, Stein TP, Scholl TO Low-normal serum selenium early in human pregnancy predicts lower birth weight.
Nutr Res . Vol. 26: 497-502
(2006
)
.
Chen X, Scholl TO, Stein TP. Association of elevated serum ferritin levels and the risk of gestational diabetes mellitus in pregnant women - Camden Study. .
Diabetes Care . Vol. 29: 1077-82
(2006
)
.
Chen X, Scholl TO. Oxidative stress: changes in pregnancy and with gestational diabetes mellitus. .
Current Diabetes Reports . Vol. 5: 282-8
(2005
)
.
Scholl TO, Leskiw M, Chen X, Sims M, Stein TP. Oxidative stress, diet and the etiology of preeclampsia..
AJCN. Vol. 81: 1390-6.
(2005
)
.
Stagnaro-Green A, Chen X, Bogden JD, Davies, TF, Scholl TO. The thyroid and pregnancy; a novel risk factor for very preterm delivery. .
Thyroid . Vol. 15: 351-7
(2005
)
.
Johnson WG, Scholl TO, Spychala JR, Stenroos ES, Chen X. Common dihydrofolate reductase 19-base pair deletion allele: a novel risk factor for preterm delivery. .
AJCN . Vol. 81: 664-8
(2005
)
.
Chen X, Scholl TO, Leskiw MJ, Donaldson MR, Stein TP. Author's response: Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. .
J Clin Endocrinol Metab . Vol. 89: 4773-4
(2004
)
.
Scholl TO, Chen X, Khoo CS, Lenders C The dietary glycemic index during pregnancy: influence on infant birth weight, fetal growth and biomarkers of carbohydrate metabolism. .
AJE . Vol. 159: 467-74
(2004
)
.
Chen X, Scholl TO, Leskiw MJ, Donaldson MR, Stein TP Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. .
J Clin Endocrinol Metab . Vol. 88: 5963-8
(2003
)
.
Scholl TO, Chen X, Gaughan C, Smith W. . Maternal glucose: influence on the ethnic difference in birth weight and pregnancy outcome. .
Am J Epidemiol . Vol. 156: 498-506
(2002
)
.
Scholl TO, Chen X. Insulin and the Thrifty Woman: the influence of insulin during pregnancy on gestational weight gain and postpartum weight retention. .
Maternal and Child Health Journal . Vol. 6: 255-61
(2002
)
.
Chen X, Scholl TO. Ethnic differences in C-peptide/insulin/glucose dynamics in young pregnant women. .
J Clin Endo Metabol . Vol. 87: 4642-6
(2002
)
.
Sowers MF, Scholl TO, Grewal J, Chen X, Jannausch M. Insulin-like growth factor-1 (IGF-1), osteocalcin and bone change in pregnant normotensive and pre-eclamptic women. .
J Clin Endocrinol Metabol 2001;86:5898-5903.. Vol. 86: 5898-5903
(2001
)
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Boden G, Chen X, Stein TP Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus. .
Am J Physiol Endocrinol Metab . Vol. 280E: 23030
(2001
)
.
Boden G, Chen X, Capulong E, Mozzoli M. Effects of free fatty acids on gluconeogensis and autoregulation of glucose production in type 2 diabetes. .
Diabetes . Vol. 50: 810-16
(2001
)
.
Homko C, Sivan E, Chen X, Reece EA and Boden G. Insulin secretion during and after pregnancy in patients with gestational diabetes mellitus. .
J Clin Endocrinol Metabol . Vol. 86: 568-73
(2001
)
.
Scholl TO, Sowers MF, Chen X, Lenders C. Maternal glucose influences fetal growth, gestation and maternal complications. .
Am J Epidemiol . Vol. 154: 514-20
(2001
)
.
Chen X, Iqbal N, Boden G. Effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects. .
J Clin Invest . Vol. 103: 365-72
(1999
)
.
Boden G and Chen X. Effects of fatty acids and ketone bodies on basal insulin secretion in type 2 diabetes..
Diabetes . Vol. 48: 577-83
(1999
)
.
Sivan E, Homko CJ, Chen X, Reece EA, Boden G. Effect of insulin on fat metabolism during and after normal pregnancy. .
Diabetes . Vol. 48: 834-38
(1999
)
.
Boden G, Chen X, Polansky M. Disruption of circadian insulin secretion is associated with reduced glucose uptake in first-degree relatives of patients with type 2 diabetes. .
Diabetes . Vol. 48: 2182-88
(1999
)
.
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Grants and Contracts
Title: Pilot Study for Epigenetics of Preterm Delivery: the influence of methyl donor & inflammation
Sponsor: Foundation of UMDNJ
Effective Date(s): 2012 - 2013
Role: PI
Title: Cardiovascular risk factors and preterm delivery
Sponsor: NIH
Effective Date(s): 2009 - 2012
Role: PI
Title: Vitamin D Status in Pregnant Women
Sponsor: NIH-NICHD
Effective Date(s): 2008 - 2012
Role: Co-PI
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Research Areas
Nutrition and metabolism : 1. Carbohydrate and lipid metabolism in type 2 diabetes, gestational diabetes and obesity
2. Causes / risk factors / mechanisms on adverse pregnancy outcomes
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