Salvatore Caradonna, PhD
Chair
Department of Molecular Biology
Associate Professor
Molecular Biology
Office Address:
Two Medical Center Drive
Science Center, Room 130
Stratford
NJ
- 08084
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Contact:
Tel: 856-566-6056
Fax: 856-566-6232
caradonn@umdnj.edu
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Education
State University of New York at Buffalo, Roswell Park Cancer Institute,
NY
PhD
(Pharmacology)
, 1980
Marist College,
NY
BA
(Biology)
, 1975
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Honors and Awards
2000, Featured in the inaugural issue of RESEARCH 2000, UMDNJ publication highlighting research within UMDNJ
1998/99, Recipient of the "Teaching and Service Incentive Award"
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Publications
Fischer, J.A., Muller-Weeks, S., Caradonna, S.J. Fluorodeoxyuridine Modulates Cellular Expression of the DNA Base Excision Repair Enzyme Uracil-DNA Glycosylase .
Cancer Research. Vol. 66: 8829-8837
(2006
September
)
.
Muller-Weeks S, Balzer RJ, Anderson R, Caradonna S. Proliferation-dependent expression of nuclear uracil-DNA glycosylase is mediated in part by E2F-4.
DNA Repair (Amst). Vol. Feb 3 2005;4(2): 183-190
(2005
)
.
Fischer JA, Muller-Weeks S, Caradonna S. Proteolytic degradation of the nuclear isoform of uracil-DNA glycosylase occurs during the S phase of the cell cycle.
DNA Repair (Amst). Vol. May 4 2004;3(5): 505-513
(2004
)
.
Elateri I, Tinkelenberg BA, Hansbury M, Caradonna S, Muller-Weeks S, Ladner RD. hSMUG1 can functionally compensate for Ung1 in the yeast Saccharomyces cerevisiae.
DNA Repair (Amst). Vol. Mar 1 2003;2(3): 315-323
(2003
)
.
Elateri I, Muller-Weeks S, Caradonna S. The transcription factor, NFI/CTF plays a positive regulatory role in expression of the hSMUG1 gene.
DNA Repair (Amst). Vol. Dec 9 2003;2(12): 1371-1385
(2003
)
.
Caradonna S, Muller-Weeks S. The nature of enzymes involved in uracil-DNA repair: isoform characteristics of proteins responsible for nuclear and mitochondrial genomic integrity.
Curr Protein Pept Sci. Vol. Dec 2001;2(4): 335-347
(2001
)
.
Ladner RD, Lynch FJ, Groshen S, Caradonna S, et al. dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer.
Cancer Res. Vol. Jul 1 2000;60(13): 3493-3503
(2000
)
.
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Grants and Contracts
Title: Post-Translational Mechanisms in Uracil-DNA Repair -
RO1 CA84421
Sponsor: NIH, National Cancer Institute
Effective Date(s): 2000 - 2005
Role: P.I.
Title: 1S15CA62298-01 Small Instrumentation Grant
Sponsor: NIH, National Cancer Institute
Effective Date(s): 1993 - 1994
Role: P.I.
Title: Genetics and Enzymology of Human DNA Repair
Sponsor: NIH, National Cancer Institute
Effective Date(s): 1990 - 1996
Role: P.I.
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Research Areas
DNA repair, cell-cycle regulatory pathways and apoptotic mechanisms induced by aberrant DNA repair mechanisms.:
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